BDK_1 (AA 213-239) antibody

Catalog No. ABIN652683

This anti- antibody is a Rabbit Polyclonal antibody detecting in FACS and WB. Suitable for Human.

Quick Overview for BDK_1 (AA 213-239) antibody (ABIN652683)

Target: BDK_1

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Flow Cytometry (FACS), Western Blotting (WB)

Clone: RB21729

Product Details

Binding Specificity: AA 213-239

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BDK_1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the Central region of human BDK_1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: BDK_1

Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. BDKRB1 is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Molecular Weight: 40495

Gene ID: 623

NCBI Accession: NP_000701

UniProt: P46663